명예교수 (M.D., Ph.D. 연세대학교)
  소화기약리, 임상약리
  2228-1732
  hwan444@yuhs.ac
 
 

1. Kim KH, Kim HY, Lee GY, Hong SS. Involvemtnt of histamine release in the mechanism of cysteamine-induced gastric acid hypersecretion. Arch Int Pharmacodyn 276(2): 379-286, 1985

2. Hong SS, Case RM, Kim KH. Analysis in the isolated perfused cat pancreas of factors implicated in the pathogenesis of pancreatitis. Pancreas 3(4):450-458, 1988

3. Thomas PE, Kim KH, Case RM, Taylor TV. Routes of enzyme secretion in the isolated perfused rat pancreas.
Digestion 46: 181, 1990

4. Seo JT, Kim SI, Kim KH, Lee SI. Effects of caffeine on calcium mobilization in rat parotid acini salivary secretion: Control and mechanisms. International Workshop on Salivary Secretion, Okazaki, Japan, p17-20, 1992


5. Ha HJ, Kim KH. Lack of influence of renin-angiotensin system on diabetic renal vasoconstriction.Asia Pacific J Pharmacol 7: 209-217, 1992

6. Ha HJ, Son YS, Chung MH, Kim KH. DNA damage in the kidney of diabetic rats exhibiting microalbuminuria. Free Radical Biol Med 16(2): 271-274, 1994

7. Ha HJ, Yoon SJ, Kim KH..High glucose can induce lipid peroxidation in the isolated glomeruli. Kidney Int 46: 1620-1626, 1994

8. Ha HJ, Kim KH. Role of oxidative stress in the development of diabetic nephropathy. Kidney International 48(suppl. 51): S-18-S-21, 1995

9. Lee SM, Kim KH. Rebamipide ameliorates hepatic dysfunction induced by ischemia/reperfusion in rats. European J Pharmacology 294: 41-46, 1995

10. Ro JY, Kim KH. Inhibition of phospholipid methylation by single component of ginsenosides durign allergic hypersensitivity. Proceedings of '95 Korean-Japan Ginseng Symposium. 121-133, 1995

11. MG Lee, KH Kim, KY Park, JS Kim. Evaluation of anti-influenza effects of camostat in mice infected with non-adapted human influenza viruses. Arch Virol 141:1979-1989, 1996

12. HY Kim, KH Kim. Hepatoprotective effect of panax ginseng against thioacetamide intoxication in rats. Asia Pacific J Pharmacol 11:91-96, 1996

13. HY Kim, KH Kim. Primary cultures of rat pancreatic acinar cells in complete media and in serum-free media.Asia Pacific J Pharmacol 11:135-140, 1996

14. HY Kim, KH Kim. Effects of a nitric oxide donor and nitric oxide synthase inhibitors on acid secretion of isolated rabbit gastric glands. Pharmacology 53:331-339, 1996

15. KH Kim, MG Lee, DG Kim. The cholecystokinin receptor antagonist L-364,718, reduces taurocholate-induced pancreatitis in rats.International J. Pancreatology 20(3):205-211, 1996


16. HY Kim, KH Kim. Ginsenosides, nitric oxide and the vascular system. JAMA Korea pp5-6, 1996

17. H Ha, KH Kim. Oxidative stress and diabetic nephropathy. JAMA Korea 12(6):5-6, 1997

18. H Ha, SH Lee, KH Kim. Effects of rebamipide in a model of experimental diabetes and on the synthesis of transforming growth factor-β and fibronectin, and lipid peroxidation induced by high glucose in cultured mesangial cells. J Pharmacol Exp Ther 281(3):1457-1462, 1997

19. H Ha, VS Kamanna, MA Kirschenbaum, KH Kim. Role of glycated low density lipoprotein in mesangial extracellular matrix synthesis. Kidney International 52, Suppl. 60, ppS-54-S-59, 1997

20. Kim H, Kim KH.Role of nitric oxide on the synthesis and secretion of mucus in gastric cells exposed to hypoxia/reoxygenation. Asia Pacific J of Pharmacology 12:109-115, 1997

21. JY Ro, BC Lee, YS Ahn, KH Kim. A single component of ginsenosides extracted from korean red ginseng radix has an adjuvant activity. 5th West-Pacific Allergy Symposium 7th Korean-Japan Allergy Symposium 11-14 June 1997 (p171-175)

22. JY Ro, KH Kim. Signal transduction of mast cells. 5th West-Pacific Allergy Symposium 7th Korean-Japan Allergy Symposium 11-14 June 1997 (p105-111)

23. KH Kim. Health implications of drug interaction. Medical Progress, 1997

24. H Kim, KH Kim.Effect of Nitric Oxide on Hydrogen Peroxide-Induced Damage in Isolated Rabbit Gastric Glands. Pharmacology 57:323-330, 1998

25. H Kim, KH Kim. Role of Nitric Oxide in Oxidative Damage in Isolated Rabbit Gastric Cells Exposed to Hypoxia-Reoxygenation.Digestive Disease & Sciences 43(5):1042-1049, 1998

26. MS Park, NC Yu, YS Kim, HK Lee, KH Kim. Bioequivalence Study of Cipol-N(Cyclosporine Microemulsion Preparation) in Healthy Adults. Transplantation Proceedings 30:3541-3546, 1998

27. JY Ro, YS Ahn, KH Kim. Inhibitory effect of ginsenoside on the mediator release in the guinea pig lung mast cells activated by specific antigen-antibody reactions. International Journal of Immunopharmacology 20:625-641, 1998

28. H Kim, KH Kim. Oxidative stress and gastric mucosal damage. Med Prog 25(8):41-45, 1998 (종설)

29. H Kim, JY Seo, KH Kim. Effects of mannitol and dimetylthiourea on Helicobacter pylori-induced IL-8 production in gastric epithelial cells. Pharmacology 59:201-211, 1999

30. H Ha, MR Yu, KH Kim. Melatonin and taurine reduce early glomerulopathy in diabetic rats. Free Radical Biology & Medicine 26:944-950, 1999

31. H Ha, KH Kim. Future of interventions in diabetic nephropathy: antioxidants. Peritoneal Dialysis International 19(Suppl 2):S230-S235, 1999

32. H Ha, KH Kim. Pathogenesis of diabetic nephropathy: the role of oxidative stress and protein kinase C. Diabetes Research and Clinical Practice 45:147-151, 1999

33. JY Ro, BC Lee, JY Kim, MH Chung, SK Lee, KH Kim, YI Park. The inhibitory mechanism of Aloe single component (Alprogen) on the mediator release in the guinea pig lung mast cells activated with specific antigen-antibody reactions. J Pharmacol Exp Ther 292(1):114-121, 1999

34. Moon SJ, Ahn W, Lee MG, Kim H, Lee SI, Seo JT, Case RM, Kim KH. A novel effect of rebamipide: generation of [Ca2+]i scillations through activation of CCK, receptors in rat pancreatic acinar cells. Eur J Pharmacol, 388:17-20, 2000

35. H Kim, JY Seo, KH Kim. Inhibition of lipid peroxidation, NF-kB activation and IL-8 production by Helicobacter pylori-stimulated gastric cells. Dig Dis Sci, 2000 45(3):621-8, 2000

36. Kim H, Seo JY, Roh KH, Lim JW, Kim KH. Suppression of NF-kappaB activation and cytokine production by N-acetylcysteine in pancreatic acinar cells. Free Radic Biol Med 29(7):674-83, 2000

37. Lee MG, Ahn W, Choi JY, Luo X, Seo JT, Schultheis PJ, Shull GE, Kim KH, Muallem S. Related Articles. Na+-dependent transporters mediate HCO3- salvage across the luminal membrane of the main pancreatic duct. J Clin Invest 105(11):1651-8, 2000

38. Ro JY, Lee BC, Kim JY, Chung YJ, Chung MH, Lee SK, Jo TH, Kim KH, Park YI. Inhibitory mechanism of aloe single component (alprogen) on mediator release in guinea pig lung mast cells activated with specific antigen-antibody reactions. J Pharmacol Exp Ther 292(1):114-21, 2000

39. Lim JW, Kim H, Kim KH. Nuclear Factor-kB Regulates Cyclooxygenase-2 Expression and Cell Proliferation in Human Gastric Cancer Cells. Lab Invest 81(3):1-12, 2001

45. Lim JW, Kim H, Kim KH: Expression of Ku70 and Ku80 Mediated by NF-kappa B and Cyclooxygenase-2 Is Related to Proliferation of Human Gastric Cancer Cells. J Biol Chem 277(48):46093-46100, 2002 Nov

46. Seo JH, Kim H, Kim KH: Cyclooxygenase-2 expression by transcription factors in Helicobacter pylori-infected gastric epithelial cells: Comparison between HP 99 and NCTC 11637. Ann NY Acad Sci 973:477-480, 2002

47. Seo JY, Kim H, Kim KH: Transcriptional regulation by thiol compounds in Helicobacter pylori-induced interleukin-8 production in human gastric epithelial cells. Ann NY Acad Sci 973:541-545, 2002

48. Ko SB, Shcheynikov N, Choi JY, Luo X, Ishibashi K, Thomas PJ, Kim JY, Kim KH, Lee MG, Naruse S, Muallem S: A molecular mechanism for aberrant CFTR-dependent HCO3- transport in cystic fibrosis. EMBO J 1;21(21):5662-72, 2002 Nov

49. Namkung W, Lee JA, Ahn W, Han W, Kwon SW, Ahn DS, Kim KH, Lee MG: Ca2+ activates CFTR- and Cl--dependent HCO3- transport in pancreatic duct cells. J Biol Chem 278(1):200-207, 2003

50. Chu SH, Kim H, Seo JY, Mukaida N, Kim KH: Role of NF-kB and AP-1 Helicobacter pylori-induced IL-8 expression in AGS cells. Dig Dis Sci 48(2):257-265, 2003

51. Hayakawa T, Naruse S, Kim KH, Go VLW: 2nd International Symposium: Frontiers in Pancreatic Research-From Basics to Clinic and Exocrine Glands, Japan-Korea. Pancreas 26(1):e1-e11, 2003

52. Lim JW, Kim H, Kim KH: Cell adhesion-related gene expression by Helicobacter pylori in gastric epithelial AGS cells. Int J Biochem Cell Biol. 35(8):1284-96, 2003 Aug

53. Lee JH, Choi JH, Namkung W, Hanrahan JW, Chang J, Song SY, Park SW, Kim DS, Yoon JH, Suh Y, Jang IJ, Nam JH, Kim SJ, Cho MO, Lee JE, Kim KH, Lee MG: A haplotype-based molecular analysis of CFTR mutations associated with respiratory and pancreatic diseases. Hum Mol Genet. 12(18):2321-32, 2003 Sep

54. Song JY, Lim JW, Kim H, Morio T, Kim KH: Oxidative stress induces nuclear loss of DNA repair proteins Ku70 and Ku80 and apoptosis in pancreatic acinar AR42J cells. J Biol Chem. 278(38):36676-87, 2003 Sep

55. Ahn W, Lee MG, Kim KH, Muallem S: Multiple effects of SERCA2b mutations associated with Darier's disease. J Biol Chem 278:20795-20801, 2003

56. Yu JH, Yun SH, Lim JW, Kim H, Kim KH: Proteome analysis of rat pancreatic acinar cells: Implication for cerulein - induced acute pancreatitis. Proteomics 3(12): 2446-2453, 2003

57. Yu JH, Yun SY, Lim JW, Kim H, Kim KH: Mass spectrometry and tandem mass spectrometry analysis of rat mitochondrial ATP synthase: Up-regulation in pancreatic acinar cells treated with cerulein. Proteomics 3(12): 2437-2445, 2003

58. Park BK, Chung JB, Lee JH, Suh JH, Park SW, Song SY, Kim H, Kim KH, Kang JK: Role of oxygen free radicals in patients with acute pancreatitis. World J Gastroenterol 9(10): 2266-2269, 2003

59. Kim H, Seo JH, Kim KH: The effect of p38 Mitogen-activated protein kinase on mucin gene expression and apoptosis in Helicobacter pylori-infected gastric epithelial cells. Ann NY Acad Sci 1010: 90-94, 2003. 12

60. Song JY, Lim JW, Kim H, Kim KH: Role of NF-kB and DNA repair protein Ku on apoptosis in pancreatic acinar cells. Ann NY Acad Sci 1010: 259-262, 2003. 12

61. Yu JH, Kim H, Kim KH: Calcium-dependent apoptotic gene expression in cerulein-treated AR42J cells. Ann NY Acad Sci 1010: 66-70, 2003.12

62. Lee J, Seo J, Kim H, Chung JB, Kim KH: Signal transduction of cerulein-induced cytokine expression and apoptosis in pancreatic acinar cells. Ann NY Acad Sci 1010: 104-108, 2003. 12

63. Chu SH, Lim JW, Kim KH, Kim H: NF-kB and Bcl-2 in Helicobacter pylori-Induced Apoptosis in Gastric Epithelial Cells. Ann NY Acad Sci 1010: 568-572, 2003.12

64. Seo JH, Lim JW, Kim H, Kim KH: Helicobacter pylori in a Korean isolate activates mitogen-activated protein kinases, AP-1, and NF-kappaB and induces chemokine expression in gastric epithelial AGS cells. Lab Invest 84(1): 49-62, 2004 Jan

65. Lim JW, Kim H, Kim KH: Protein synthesis, post-translation modification, and degradation: The Ku antigen-RBP-Jk complex binds to NF-kB p50 promoter and acts as a positive regulator of p50 expression in human gastric cancer cells. J Biol Chem 279(1): 231-237, 2004

66. Kim JY, Han WS, Namkung W, Lee JH, Kim KH, Shin H, Kim E, Lee MG: Inhibitory regulation of cystic fibrosis transmembrane conductance regulator anion-transporting activities by Shank2. J Biol Chem 279(11): 10389-10396, 2004

67. Lim JW, Kim H, Kim JM, Kim JS, Jung HC, Kim KH: Cellular stress-related protein expression in Helicobacter pylori-infected gastric epithelial AGS cells. Int J Biochem Cell B 36: 1624-1634, 2004

68. Namkung W, Han WS, Luo X, Muallem S, Cho KH, Kim KH, Lee MG: Protease-activated receptor 2 exerts local protection and mediates part of systemic complications in acute pancreatitis. Gastroenterology 126: 1844-1859, 2004

69. Baek HY, Lim JW, Kim H, Kim JM, Kim JS, Jung HC, Kim KH: Oxidative stress-related proteome changes in Helicobacter pylori-infected human gastric mucosa. Biochem J 379: 291-299, 2004

70. Yu JH, Lim JW, Kim H, Kim KH: NADPH oxidase mediates interleukin-6 expression in cerulein-stimulated pancreatic acinar cells. Int J Biochem Cell Biol 37: 1458-1469, 2005

71. Yu JH, Lim JW, Kim KH, Morio T, Kim H: NADPH oxidase and apoptosis in cerulein-stimulated pancreatic acinar AR42J cells. Free Rad Biol & Med 39: 590-602, 2005

72. Namkung W, Kim KH, Lee MG: Base treatment corrects defects due to misfolding of mutant cystic fibrosis transmembrane conductance regulator. Gastroenterology 129: 1979-1990, 2005

73. Han WS, Kim KH, Jo MJ, Lee JH, Yang J, Doctor RB, Moe OW, Lee J, Kim EJ, Lee MG: Shank2 associates with and regulates Na+/H+ exchanger 3. J Biol Chem 281(3): 1461-1469, 2006

75. Yu JH, Kim KH, Kim H: Suppression of IL-1β expression by the Jak 2 inhibitor AG490 in cerulein-stimulated pancreatic acinar cells. Biochem Pharm 72:1555-1562, 2006

76. Ju KD, Yu JH, Kim H, Kim KH: Role of mitogen-activated protein kinases, NF-kB and AP-1 on cerulein-induced IL-8 expression in pancreatic acinar cells. Ann NY Acad Sci, 1090: 368-374, 2006

77. Yu JH, Kim KH, Kim H: Role of NADPH oxidase and Calcium in Cerulein-Induced Apoptosis : Involvement of Apoptosis-Inducing Factor. Ann NY Acad Sci, 1090:292-297, 2006

78. Cho SO, Kim KH, Yoon JH, Kim H: Signaling for integrin α5/β1 expression in Helicobacter pylori infected gastric epithelial AGS cells. Ann NY Acad Sci, 1090: 298-304, 2006

79. Lee JH, Kim KH, Morio T, Kim H: Ataxia-telangiectasia-mutated=dependent activation of Ku in human fibroblasts exposed to hydrogen peroxide. Ann NY Acad Sci, 1091: 76-82, 2006

80. Lee J, Kim KH, Kim H: Role of vascular endothelial growth factor-D (VEGF-D) on IL-6 expression in cerulein-stimulated pancreatic acinar cells. Ann NY Acad Sci, 1095: 129-133, 2007

81. Cha B, Kim KH, Matsui H, Kim H: Expression of Suppressors of Cytokine Signaling-3 (SOCS-3) in Helicobacter pylori-Infected Rat Gastric Mucosal RGM-1 Cells. Ann NY Acad Sci 1096: 24-28, 2007

82. Seo JH, Kim KH, Kim H: Role of Proteinase-Activated Receptor-2 on Cyclooxygenase-2 Expression in H. pylori - Infected Gastric Epithelial Cells. Ann NY Acad Sci 1096: 29-36, 2007

83. Park K, Kim YS, Kwon KI, Park MS, Lee YJ, Kim KH: A randomized, open-label, two-period, crossover bioavailability study of two oral formulations of tacrolimus in healthy korean adults. Clin Ther 29(1): 154-162, 2007

84. Choi JH, Ahn BM, Yi J, Lee JH, Lee JH, Nam SW, Chon CY, Han KH, Ahn SH, Jang IJ, Cho JY, Suh Y, Cho MO, Lee JE, Kim KH, Lee MG: MRP2 haplotypes confer differential susceptibility to toxic liver injury. Pharmacogenet Genom 17(6): 403-415. 2007

85. Kim J, Jung YS, Han WS, Kim MY, Namkung W, Lee BH, Yi KY, Yoo S, Lee MG, Kim KH: Pharmacodynamic characteristics an cardioprotective effects of new NHE1 inhibitors. Eur J Pharmacol 567:131-138, 2007

86. Yu JH, Kim KH, Kim DG, Kim H: Diphenyleneiodonium suppresses apoptosis in cerulein-stimulated pancreatic acinar cells. Int J Biochem Cell B 39: 2063-2075, 2007

87. Lee JH, Richter W, Namkung W, Kim KH, Kim E, Conti M, Lee MG: Dynamic regulation of cystic fibrosis transmembrane conductance regulator by competitive interactions of molecular adaptors. J Biol Chem 282(14): 10414-10422, 2007

88. Choi JH, Lee YJ, Jang SB, Lee JE, Kim KH, Park K: Influence of the CYP3A5 and MDR1 genetic polymorphisms on the pharmacokinetics of tacrolimus in healthy Korean subjects. Brit J Clin Pharmaco 64(2): 185-191, 2007

89. Yu JH, Seo JY, Kim KH, Kim H: Differentially expressed proteins in cerulein-stimulated pancreatic acinar cells: Implication for acute pancreatitis. Int J Biochem Cell B 40: 503-516, 2008

90. Yu JH, Kim KH, Kim H: SOCS 3 and PPAR-γ ligands inhibit the expression of IL-6 and TGF-β1 by regulating JAK2/STAT3 signaling in pancreas. Int J Biochem Cell B 40: 677-688, 2008

91. Choi JH, Lee MG, Cho JY, Lee JE, Kim KH, Park K(교신저자): Influence of OATP1B1 genotype on the pharmacokinetics of rosuvastatin in Koreans. Clin Pharmacol Ther 83(2): 251-257, 2008

92. Yoon JS, Park HJ, Yoo SY, Namkung W, Jo MJ, Koo SK, Park HY, Lee WS, Kim KH, Lee MG: Heterogeneity in the processing defect of SLC26A4 mutants. J Med Genet 45:411-419, 2008

93. Lim JW, Kim KH, Kim H: NF-kB p65 regulates nuclear translocation of Ku70 via degradation of heat shock cognate protein 70 in pancreatic acinar AR42J cells. Int J Biochem Cell B 40:2065-2077, 2008

94. Namkung W, Yoon JS, Kim KH, Lee MG: PAR2 exerts local protection against acute pancreatitis via modulatoin of MAP kinase and MAP kinase phosphatase signaling. Am J Physiol Gastrointest Liver Physiol 295:G886-G894, 2008

95. Lee JH, Lee W, Kwon OH, Kim JH, Kwon OW, Kim KH, Lim JB: Cytokine profile of peripheral blood in type 2 diabetes mellitus patients with diabetic retinopathy. Ann Clin Lab Sci 38(4):361-367, 2008

96. Sohn MY, Lee JH, Kim KW, Kim SW, Lee SH, Kim KE, Kim KH, Lee CG, Elias JA, Lee MG: Genetic Variation in the Promoter Region of Chitinase 3-Like 1 Is Associated with Atopy. Am J Respir Crit Care Med 179: 449-456, 2009

97. Gee HY, Kim YW, Jo MJ, Namkung W, Kim JY, Park HW, Kim KS, Kim HG, Baba A, Yang J, Kim E, Kim KH, Lee MG: Synaptic scaffolding molecule binds to and regulates vasoactive intestinal polypeptide Type-1 receptor in epithelial cells. Gastroenterology 137: 607-617, 2009

98. Kim J, Namkung W, Yoon JS, Jo MJ, Lee SH, Kim KH, Kim JY, Lee MG: The role of translation elongation factor eEF1A in intracellular alkalinization-induced tumor cell growth. Lab Invest 89(8): 867-874, 2009

99. Cha B, Kim KH, Kim H: 15-Deoxy-Δ,12,14-prostaglandin J2 suppresses nuclear factor-κB-mediated apoptosis of Helicobacter pylori-Infected gastric epithelial cells. Ann NY Acad Sci 1171: 457-463, 2009

100. Lim JW, Song JY, Seo JY, Kim H, Kim KH: Role of pancreatitis-associated protein 1 on oxidatives stress-Induced cell death of pancreatic acinar cells. Ann NY Acad Sci 1171: 545-548, 2009

101. Lim JW, Kim KH, Kim H: alpha Pix interacts with Helicobacter pylori CagA to induce IL-8 expression in gastric epithelial cells. Scand J Gastroenterol 44(10): 1166-1172, 2009

102. Chung JY, Lee YJ, Jang SB, Lim LA, Park MS, Kim KH: CYP3A5*3 genotype associated with intrasubject pharmacokinetic variation toward tacrolimus in bioequivalence study. Ther Drug Monit 32(1): 67-72, 2010

103. Lee JS, Lee YM, Kim JY, Park HW, Grinstein S, Orlowski J, Kim E, Kim KH, Lee MG: βPix up-regulates Na+/H+ exchanger 3 through a Shank2-mediated protein-protein interaction. J Biol Chem 285(11):8104-8113, 2010

104. Kwak JO, Lee SH, Lee GS, Kim MS, Ahn YG, Lee JH, Kim SW, Kim KH, Lee MG: Selective inhibition of MDR1 (ABCB1) by HM30181 increases oral bioavailability and therapeutic efficacy of paclitaxel. Eur J Pharmacol 627: 92-98, 2010

105. Jang SB, Lee YJ, Lim LA, Park KM, Kwon BJ, Woo JS, Kim YI, Park MS, Kim KH, Park K,: Pharmacokinetic comparison of controlled-release and immediate-release oral formulations of simvastatin in healthy korean subjects: A randomized, open-label, parallel-group, single- and multiple-dose study. Clinical Therapeutics 32(1): 206-216, 2010

106. Cho SO, Lim JW, Kim KH, Kim H: Involvement of ras and AP-1 helicobacter pylori-induced expression of COX-2 and iNOS in gastric epithelial AGS cells. Dig Dis Sci 55: 988-996, 2010

107. Kim WJ, Lee JH, Yi J, Cho YJ, Heo K, Lee SH, Kim SW, Kim MK, Kim KH, Lee BI, Lee MG: A nonsynonymous variation in MRP2/ABCC2 is associated with neurological adverse drug reactions of carbamazepine in patients with epilepsy. Pharmacogenetics and Genomics 20: 249-256, 2010

108. Cha B, Lim JW, Kim KH, Kim H: HSP90β interacts with Rac1 to activate NADPH oxidase in Helicobacter pylori-infected gastric epithelial cells. Int J Biochem Cell Biol 42: 1455-1461, 2010

109. Park HW, Nam JH, Kim JY, Namkung W, Yoon JS, Lee JS, Kim KS, Venglovecz V, Gray MA, Kim KH, Lee MG: Dynamic regulation of CFTR bicarbonate permeability by [Cl-]i and Its role in pancreatic bicarbonate secretion. Gastroenterology 139:620-631, 2010

110. Cho SO, Lim JW, Jun JH, Kim KH, Kim H: Helicobacter pylori in a Korean isolate expressed proteins differentially in human gastric epithelial cells. Digest Dis Sci 55: 1550-1564, 2010

111. Kim KW, Lee JH, Lee MG, Kim KH, Sohn MH, Kim KE: Association between Cystic Fibrosis Transmembrane Conductance Regulator Gene Mutations and Susceptibility for Childhood Asthma in Korea. Yonsei Med J 51(6):912-917, 2010

112. Gee HY, Tang BL, Kim KH, Lee MG: Syntaxin 16 Binds to Cystic Fibrosis Transmembrane Conductance Regulator and Regulates Its Membrane Trafficking in Epithelial Cells. The Journal of biological chemistry 285:35519-35527, 2010

113. Gee HY, Kim CK, Kim SW, Lee JH, Kim JH, Kim KH, Lee MG: The L441P mutation of cystic fibrosis transmembrane conductance regulator and its molecular pathogenic mechanisms in a Korean patient with cystic fibrosis. J Korean Med Sci 25(1): 166-171, 2010

114. Gee HY, Noh SH, Tang BL, Kim KH, Lee MG: Rescue of DF508-CFTR Trafficking via a GRASP-Dependent Unconventional Secretion Pathway. Cell 146: 746-760, 2011

115. Park HW, Kim JY, Choi SK, Lee YH, Zeng W, Kim KH, Muallem S, Lee MG: Serine-threonine kinase with-no-lysine 4 (WNK4) controls blood pressure via transient receptor potential canonical 3 (TRPC3) in the vasculature. PNAS 108(26):10750-10755, 2011

116. Lee JH, Kim KW, Gee HY, Lee J, Lee K, Park HS, Kim SH, Kim SW, Kim M, Kim KE, Kim KH, Lee MG, Shon MH: A synonymous variation in protease-activated receptor-2 is associated with atopy in Korean children. J Allergy Clinical Immunology 128(6): 1326-1334, 2011

117. Chu SH, Lim JW, Kim DG, Lee ES, Kim KH, Kim H: Down-regulation of Bcl-2 is mediated by NF-kB activation in Helicobacter pylori-induced apoptosis gastric epithelial cells. Scand J Gastroentero 46: 148-155, 2011

118. Cho SO, Lim JW, Kim KH, Kim H: Diphenyleneiodonium inhibits the activation of mitogen-activated protein kinases and the expression of monocyte chemoattractant protein-1 in Helicobacter pylori-infected gastric epithelial AGS cells. INFLAMMATION RESEARCH 60(5): 501-507, 2011

119. Cha BR, Lim JW, Kim KH, Kim H: 15-Deoxy-delta 12, 14-prostaglandin J2, NADPH oxidase, and RANTES expression in Helicobacter pylori-infected gastric epithelial cells. JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY 62(2): 167-174, 2011

120. Chung WY, Park HW, H대 DK, Kim KH, Lee MG, Kim JY: WNK4 kinase negatively regulates the surface expression of Muscarinic M3 receptor. CELLULAR SIGNALLING 23(3): 566-571, 2011

121. Ju KD, Lim JW, Kim KH, Kim H: Potential role of NADPH oxidase-mediated activation of Jak2/Stat3 and mitogen-activated protein kinases and expression of TGF-b1 in the pathophysiology of acute pancreatitis. Inflammation Research 60: 791-800, 2011



1. Studies on pancreatic enzyme-fractionation by electrophoresis and isoelectric focusing.
Kim WJ, Kim KH, Hong SS
J Koran Med Asso 15: 787-795, 1972

2. Experimental studies on toxicity of L-Asparaginase to pancreas.
Hong SS, Kim WJ, Kim KH, Kim HK, Kim CS, Kim DH, YW
Korean J Int Med 16: 485-491, 1973

3. Studies on early changes of exocrine pancreatic function in experimental pancreatitis.
Kim KH
J Korean Med Assoc 16: 973-981, 1973

4. Studies on drug matabolism in fetal and developmental stages.
Kim KH, Shideman FE, Lee WC
J Korean Med Assoc 16: 383-388, 1973

5. Effect of bile acids on biliary excretion of cholesterol in rabbits.
Hong SS, Kim KH, Kim WJ
Yonsei Med J 14:109-115, 1973

6. 원반전기영동법을 이용한 전립선액의 단백분리에 관한 연구.
이진무, 김경환, 김원준:
대한약리학잡지 10(2): 5-8, 1974

7. 취장효소의 신소장에 관한 연구.
권성원, 왕종순, 김경환, 홍사석
대한비뇨기과학회잡지 16(1): 11-24, 1975

8. Studies on venerupin shellfish poison in Korea.
Hong SS, Kim WJ, Kim KH, Lee YB
Korean J Gastroenterol 7(2): 39-55, 1975

9. Experimental studies on the pathegenesis of acute pancreatitis.
Hong SS, Kim KH, Kim WJ, Kim SH, Kim CS, Lee YB
Korean J Gastroenterol 7(1): 1-23, 1975

10. 담즙산염과 간장.
홍사석, 김경환
한국의과학 7(6): 353-364, 1975

11. 취장 및 간장 외분비기능에 대한 교감신경성 영향.
김경환, 홍사석
연세의대 논문집 10(1): 16-28, 1977

12. 농약으로 인한 간취 외분비 변동.
김학혜, 김경환, 홍사석
연세의대 논문집 10(2): 170-180, 1977

13. 지속분비 자극이 취효소 배출에 미치는 영향.
배영숙, 김경환, 홍사석
연세의대 논문집 11(2): 31-39, 1978

14. 지속분비 자극이 취효소 배출에 미치는 영향.
윤견일, 김경환, 홍사석
연세의대 논문집 11(2): 55-67, 1978

15. Effect of β-Adrenergic blockers on experimentally-induced convulsion and narcosis.
Huh S, Kim KH, Hong SS
Yonsei Med J 19(1): 25-31, 1978

16. Histamine의 위 평활근 수축운동에 관한 약리학적 검색.
유시옥, 김경환, 홍사석
연세의대 논문집 13(2): 145-156, 1980

17. Effects of pancreatic polypeptide on the secretion of enzymes and electrolytes by in vitro preparatins of rat and cat pancreas.
Kim KH, Case RM
Yonsei Med J 21(2): 99-105, 1980

18. 타액선 외분비기능의 약리학적 검색.
조행작, 김경환, 홍사석
연세의대 논문집 14(2): 273-287, 1981

19. 알콜의 농도 및 투여 경로에 따른 위산분비변동.
김동구, 박형숙, 김경환, 홍사석
대한약리학회지 17(1): 27-32, 1981

20. Trypsin 및 담즙산이 적출취장 외분비 기능에 미치는 영향.
김경환, 김동구, 홍사석
대한의학협회지 24(9): 793-801, 1981

21. 생체외 실험적 취장염에 관한 연구.
이우형, 김경환, 홍사석
연세의대 논문집 14(2): 234-248, 1981

22. 취효소분비에 미치는 aminoglycosides의 영향.
김성규, 최홍재, 김경환, 홍사석
대한내과학회지 25(5): 493-503, 1982

23. 이뇨제가 취장 외분비기능에 미치는 영향.
이철, 윤덕진, 김경환, 김원준
연세의대 논문집 15(2): 165-176, 1982

24. Prostaglandin이 위산분비에 미치는 영향.
권순대, 김경환, 홍사석
연세의대 논문집 15(2): 10-23, 1982

25. 산조인의 중추신경 및 심혈관계에 대한 약리작용.
안영수, 김경환, 조태순, 김원준, 홍사석
대한약리학회지 18(1): 921-926, 1982

26. Aminoglycosides의 취효소 분비항진 기전에 관한 연구.
심호식, 김경환, 홍사석
대한약리학회지 19(1): 71-76, 1983

27. Cysteamine의 십이지장궤양 발생기전에 관한 연구.
이강용, 김경환, 김혜영, 홍사석
연세의대 논문집 16(2): 291-301, 1983

28. Ethionine으로 인한 취장외분비부전에 관한 연구.
최홍열, 김경환, 홍사석
연세의대 논문집 16(1): 292-395, 1983

29. 진통제의 약리.
김경환
연세대학교 의과대학 가정의학 보수교육, 1983

30. 방광 평활근 운동에 대한 펩타이드 전달 인자의 영향.
신동철, 고창만, 김경환, 홍사석
연세의대 논문집 17(2): 428-439, 1984

31. 아드레나린성 약물 전처치 흰쥐의 취절편 효소분비에 관한 실험.
김경환, 김혜영, 안영수, 이우주, 홍사석
대한약리학회지 20(2): 49-57, 1984

32. 취효소 인자 (lipase, phospholipase A 및 elastase)관류로 인한 적출 취장의 외분비 변동.
김종호, 김경환, 홍사석
연세의대 논문집 17(1): 41-55, 1984

33. 위산분비기능의 부교감신경성 영향에 관한 약리학적 검토.
김창호, 김혜영, 김경환, 홍사석
연세의대 논문집 18(1): 69-79, 1985

34. Vasoactive intestinal polypeptide의 자궁수축운동 억제기전에 관한 연구.
윤태기, 김예식, 김경환, 홍사석
연세의대 논문집 19(2): 285-296, 1986

35. 취효소 분비에 대한 부신피질혼몬의 영향.
윤태연, 김경환, 김춘규, 홍사석
연세의대 논문집 19(2):297-307, 1986

36. 취장 외분비기능에 대한 체내 amines의 역할.
곽정재, 김예식, 명창선, 김경환
연세의대 논문집 20(2): 234-243, 1987

37. Neurotensin이 자궁 평활근 운동에 미치는 영향.
한원보, 김예식, 김경환, 홍사석
연세의대 논문집 20(1): 196-205, 1987

38. 고양이 적출 취장 외분비 기능에 대한 난소 홀몬의 영향.
최재원, 김경환
연세의대 논문집 20(2): 445-451, 1987

39. 본태성고혈압 환자에서 저염식 및 교감신경차단제 사용시 요중 catecholamines 함량 변동.
장중현, 조영호, 이경미, 신길자, 이우형, 안영수, 김동구, 김경환, 홍사석
대한내과학회잡지 34(4): 511-518, 1988

40. Calcium 및 potassium이 적출 이자의 효소유리에 미치는 영향.
김경환, 김동구, 김예식, 이선미, 안영수, 홍사석
대한소화기병학회잡지 20(2): 311-320, 1988

41. 파킨슨씨병 환자에 있어서 자가부신수질 이식술.
정상섭, 박상근, 오성훈, 김선호, 윤도흠, 박정수, 양우익, 최인준, 안영수, 김경환, 박창일, 김진수, 이현철
대한신경의과학회지 17(6): 1331-1342, 1988

42. 생콩투여가 흰쥐 췌장의 외분비 기능 및 미세구조에 미치는 영향.
김경환, 김동구, 이선미, 안영수, 김완종, 등영건
원주의대 논문집 1(1): 65-76, 1988

43. 뇌실내 calcitonin 투여가 위산분비에 미치는 영향에 관한 연구.
장우익, 권상옥, 연규홍, 고창만, 이상인, 최홍재, 안영수, 김경환, 홍사석
대한소화기병학회잡지21(4): 807-817, 1989

44. 두부외상후 정신과환자의 척수액 catecholamine 변동에 관한 연구.
신정호, 김경환, 안영수, 배안
대한의학협회지 32(4): 413-420, 1989

45. Vasoactive intestinal polypeptide의 뇌실내 투여가 위산분비 및 위궤양 발생에 미치는 영향.
김양우, 최재원, 안영수, 김경환
대한소화기병학회잡지 21(1): 1-11, 1989

46. 생콩을 첨가 사육한 흰쥐의 이자외분비 기능 및 구조에 관한 연구.
김학산, 주일로, 안영수, 김경환
대한소화기병학회지 22: 939-952, 1990

47. 이자외분비 기능에 대한 갑상선 홀몬의 영향.
김기수, 이민구, 김경환
대한소화기병학회지 23(3): 737-749, 1991

48. 사람 이자 효소단백의 HPLC분석.
이민구, 김경환
대한소화기병학회지 24(6): 1423-1433, 1991

49. 합성 typsin 억제제 camostat에 의한 이자외분비 기능 변동 기전에 관한 연구.
김경환, 이민구, 방영옥
대한소화기병학회지 24: 593-604, 1992

50. 뇌실내 TRH(thyrotropinpreleasing hormone)에 의한 이자외분비 항진 기전에 대한 연구.
이경은, 류병훈, 최재원, 안영수, 김경환
대한소화기병학회지 24: 1411-1422, 1992

51. Amelioration of diabetic microalbuminuria and lipid peroxidation by captopril.
Ha HJ, Kim KH
Yonsei Med J 33: 217-223, 1992

52. 당뇨성 신장질환의 발생기전에 관여하는 reninpangiotensin계의 역할.
하헌주, 우호철, 김경환
대한신장학회지 11: 89-100, 1992

53. 실험적 뇌허혈로 인한 신경전달 물질 변동 및 이에 대한 Nimodipine의 효과.
박용기, 서정택, 방혜련, 김경환
대한신경과학회지 10(4):515-530, 1992

54. Peptic ulcer disease: recent advances in treatment.
Kim KH
Medical Progress Feb: 5-9, 1992

55. Effects of cromakalim on the release of mediators in hypersensitivity of guinea pig.
Ro JY, Kim KH
Korean J Pharmacol 29(2): 263-274, 1993

56. 허혈 재관류로 인한 뇌조직 아민 변동과 free radical과의 관련성.
이경은, 김경환
대한신경화학회지 11(3): 329-340, 1993

57. Effects of panax ginseng saponins on chemical mediator release from airway smooth muscle in actively sensitized guinea pig.
Ro JY, Yoon SJ, Lee JW, Kim KH
Proc Int'l Ginseng Symposium 6: 84-94, 1993

58. Effects of amiloride on A1 adenosine receptor adenyly cyclase syste in rat adipocytes.
Park KS, Lee MS, Kim KH
Korean J Pharacol 29(2): 245-252, 1993

59. Regulation of insulinpsensitive cyclic nucleotide phosphodiesterase in adipocytes of streptozotocin-induced diabetic rats.
Park KS, Lee MS, Kim KH
Korean J Pharmacol 29(2): 253-251, 1993

60. 식이성 w3/w6 지방산이 흰쥐 뇌조직의 신경전달물질 농도에 미치는 영향.
정은정, 이경은, 방혜련, 김경환, 김진수, 이양자
대한신경과학회지 11(4): 1993

61. 인삼 사포닌 단일물질이 알러지 과민반응의 매개체 유리기전에 미치는 영향.
노재열, 김경환
Korean J Pharmacol 30(2): 243-254, 1994

62. Camostat 투여 흰쥐 이자 외분비선의 분비자극물질에 대한 반응성.
김철, 김동구, 김경환
Korean J Pharmacol 30(2):P 205-215, 1994

63. 방사선 조사후 흰쥐 췌장 외분비선의 조기 변화와 췌장염 유발에 관한 연구.
김남규, 이경식, 이민구, 김경환
대한소화기학회지 26(4): 716-717, 1994

64. 약물의 부작용.
김경환
대한의학협회지 37(10): 1160-1164, 1994

65. Effects of epithelium on the mechanism of mediator release from guinea pig tracheal tissues sensitized by IgG1 versus IgE antibody.
Ro JY, Kim KH
Yonsei Medical Journal 36(2): 161-174, 1995

66. Acid secretion and nitric oxide synthase activity in gastric glands following hypoxia/reoxygenation and acidosis.
Kim HY, Kim KH
Korean J Pharmacol 31(1): 75-84, 1995

67. 흰쥐에서 생애초기의 스트레스 경험이 성숙후 신경행동에 미치는 영향.
김원주, 이서울, 김동구, 김경환
Korean J Pharmacol 31(2): 179-194, 1995

68. Protective effect of nicotine on gastrin-induced gastric mucosal damage in rats.
Piao SH, Kim DG, Jin DN, Wu ZJ, Hong CL, Kim KH
Korean J Pharmacol 31(3): 313-321, 1995

69. 이자효소 분비에 관여하는 세포내 조절 단백에 대한 연구.
정구용, 김경환
연세의대 학위논문집 415-430, 1995

70. Oleic acid 유발 흰쥐 이자 기능부전에 대한 camostat 및 cholecystokinin의 효과.
김경환, 김동구, 이민구, 김철, 이정은
대한소화기학회지 27(1)96-109, 1995

71. Induction of heat shock protein 70 inhibits tumor necrosis factor α-induced lipid peroxidation in rat mesangial cells.
Ha H, Park YM, Kim KH
Kor J Pharmacol 31(3):323-331, 1995

72. Biochemical analysis of initial triggering events of mediator release from activated mast cells.
Ro JY, Kim KH
알레르기 15(1):51-68, 1995

73. 뇌허혈 재관류로 인한 뇌조직 아민 변동과 nitric oxide 및 산소유리기와의 관련성.
문준식, 정희선, 김동구, 김경환, 이병철
대한신경과학회지 13(4):773-787, 1995

74. 정상 성인에서 Cyclosporine 연질 경구제제 네오프란타의 생물학적 동등성에 관한 연구.
유내춘, 나대로, 박민수, 김경환
임상약리학회지 4(2):129-138, 1996

75. Cholecystokinin 길항제인 L-364,718이 시험관내 췌장암세포 성장에 미치는 영향.
송시영, 정재복, 강진경, 박인서, 김경환
대한소화기학회지 28(6):861-873, 1996

76. Melatonin.
김경환
대한의학협회지 39(8):1009-101, 1996

77. 이자효소 분비에 관여하는 세포내 조절 단백에 대한 연구.
정구용, 최재원, 최홍순, 김경환
Kor J Pharmacol 32(2):243-257, 1996

78. Role of nitric oxide as an antioxidant in the defense of gastric cells.
HY Kim, EJ Lee, KH Kim
Kor J Pharmacol 32(3):389-397, 1996

79. Thioacetamide 유발 흰 쥐 간독성에 대한 인삼 사포닌 및 에타놀 추출물의 효과.
김혜영, 최홍순, 김경환
Korean J. Toxicol 12(2):251-258, 1996

80. The effects of cromakalim on the mediator releases from guinea pig lung mast cell activated by specific antigen-antibody reactions.
JY Ro, YN Yim, KH Kim
YMJ 37(5):325-338, 1996

81. Secretory response of cultured acinar cells of rat pancreas to cholecystokinin.
HY Kim, KH Kim
YMJ 37(6):405-411, 1996

82. 흰쥐 이자에서 Secretin-CCK 상승작용 기전에 관한 연구.
이동기, 김준명, 권상옥, 박경선, 정재복, 강진경, 김경환
대한소화기학회지 29(3):380-393., 1997

83. Bioequivqlence study of CIPOL-N (Cyclosporine Microemulsion Preparation) in healthy adults.
MS Park, NC Yu, DR Na, YS Kim, KH Kim
대한이식학회지 11(1):109-117, 1997

84. 당뇨병성 신증의 발생과 진행에 관여하는 산화성 스트레스의 역할.
하헌주, 김경환
대한신장학회지 16(2):S134-S139, 1997

85. Effects of ginsenosides on the mechanism of histamine release in the guinea pig lung mast cells activated by specific antigen-antibody reactions.
JY Ro, YS Ahn, KH Kim
Korean J Physiol Pharmacol 1:445-456, 1997

86. 저산소/재산소화와 sodium nitroprusside가 분리 위선세포의 산분비 및 세포내 cyclic nucleotide에 미치는 영향.
김혜영, 이송철, 김경환
대한소화기학회지 29(2):164-174, 1997

87. 분리 위선세포에서 가역성 프로톤 펌프 억제제 YH1238 및 YH1885의 위산분비 억제효과.
김혜영, 김동구, 이봉용, 이종욱, 김경환
Korean J Phsiol Pharmacol 1:337-343, 1997

88. 해명 폐조직 비반세포가 항원-항체 반응에 의해 활성화시 매체 유리에 미치는 Ginsenoside(Rb1)의 기전 연구.
노재열, 안영수, 김경환
천식 및 알레르기 18(2):252-267, 1998

89. 마우스, 랫트, 해명에서 집먼지 진드기 추출물의 일반 약리시험과 급성 및 아급성 독성에 관한 연구.
노재열, 김경환
J. Toxicol. Pub. Health 14(2):183-191, 1998

90. 뇌실내 Thyrotropin-releasing Hormone이 위배출 기능에 미치는 영향.
김범수, 김영수, 박효진, 김경환, 강진경, 박인서
대한소화기학회지 32(4):417-426., 1998

91. 인체 및 토끼 위선세포에서 인삼사포닌의 위산분비 매개 신호전달체계에 미치는 영향.
김혜영, 김신일, 김경환
고려인삼학회지 22(1):22-31, 1998

92. Cromakalim blocks membrane phosphoinositide activated signals in the guinea pig lung mast cells stimulated with antigen-antibody reactions.
JY Ro, JY Kim, KH Kim
Kor J Physiol Pharmacol 2:251-260, 1998

93. The inhibitory mechanism of aloe glycoprotein (NY945) on the mediator release in the guinea pig lung mast cell activated with antigen-antibody complexes.
JY Ro, BC Lee, MH Chung, SK Lee, CK Sung, KH Kim, YI Park
Kor J Physiol Pharmacol 2:119-131, 1998

94. Protective mechanism of nitric oxide and mucus against ischemia/reperfusion-induced gastric mucosal injury.
H Kim, K Nam, KH Kim
Kor J Physiol Pharmacol 2:511-519, 1998

95. Effects of small molecular antioxidants on cerulein-induced acute pancreatitis in rat.
JY Choi, KH Kim
Kor J Physiol Pharmacol 2:629-635, 1998

96. Loxoprofen sodium 제제(레녹스정)의 생물학적 동등성 시험.
최주영, 유내춘, 박민수, 김경환
응용약물학회지 6:417-422, 1998

97. 의학교육 및 의료에 대한 의과대학생의 의식.
김경환, 박정한
대한의사협회지 42(3):234-237, 1999

98. 콜린결핍 에치오닌 강화식이로 유발한 췌장염에서 저분자 항산화 물질의 효과.
최주영, 조영업, 노관호, 김경환
대한소화기학회지 33:697-707, 1999

99. Lipid peroxidation, NF-kB activation and cytokine production in neutrophil-stimulated pancreatic acinar cells.
H Kim, JY Seo, SH Cho, KH Kim
Kor J Physiol Pharmacol 3:521-528, 1999

100. 의과대학생의 의학교육 및 의료에 대한 의식 조사: 1. 조사방법 및 조사대상자의 특징.
박정한, 김경환, 전혜리, 박순우
한국의학교육 11(2):339-363, 1999

101. 의과대학생의 의학교육 및 의료에 대한 의식 조사: 2. 졸업후 진로에 대한 계획.
박정한, 김경환, 전혜리, 박순우
한국의학교육 11(2):365-378, 1999

102. 의과대학생의 의학교육 및 의료에 대한 의식 조사: 3. 의사의 사회적 지위, 의료실태 및 의료체계 등에 대한 의대생의 견해.
박정한, 김경환, 전혜리, 박순우
한국의학교육 11(2):379-395, 1999

103. Immunomedulating action of ginsenosides in immune responses of specific antigens.
JY Ro, JY Kim, KH Kim
Int Kor-Jap Ginseng 4:163-174, 1999

104. 김경환: 약물의 생물학적 동등성 평가. 대한의사협회지 45(1):65-72, 2002 Jan

105. Lee MG, Kim JW, Kim KH, Muallem S: Molecular mechanism of pancreatic bicarbonate secretion.Kor J Physiol Pharmacol 6:131-138, 2002 June

106. 김경환: 소화제의 적응증. 대한의사협회지 46(2):124-128, 2003 Feb

107. 서정연, 김경환, 김혜영: Helicobacter pylori에 감염된 AGS 세포에서 IL-8 발현에 대한 산화감지 전사인자의 역할.
Korean Journal of Helicobacter and Upper Gastrointestinal Research 5(2):124-133, 2005

108. Gee HY, Kim CK, Kim SW, Lee JH, Kim JH, Kim KH, Lee MG: The L441P mutation of cystic fibrosis transmembrane conductance regulator and its molecular pathogenic mechanisms in a Korean patient with cystic fibrosis. J Korean Med Sci 25(1): 166-171, 2010

 
 
 
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