1. Song
MJ, Kim HK, Lee ST, Kim YG, Seo SY, Park
JM, Choi JW, Jang HW, Shin JH, Min SW, Zhejiu
Quan, Kim JH, Kang HC, Yoon S, Kim H+. (Corresponding
author). Sequence-specific prediction of
the efficiencies of adenine and cytosine
base editors.
Nat. Biotechnol. 2020 ; doi: 10.1038/s41587-020-0573-5.
[Online ahead of print]
2. Kim N, Kim HK, Lee ST, Seo JH, Choi
JW, Park J, Min SW, Yoon S, Cho SR, Kim
H+. (Corresponding author). Prediction of
the sequence-specific cleavage activity
of Cas9 variants.
Nat. Biotechnol. 2020; doi : 10.1038/s41587-020-0537-9.
[Online ahead of print]
3. Kim HK, Lee S, Kim Y, Park J, Min S,
Choi JW, Huang TP, Yoon S, Liu DR, Kim H+
(+Corresponding author). High-throughput
analysis of the activities of xCas9, SpCas9-NG
and SpCas9 at matched and mismatched target
sequences in human cells.
Nat Biomed Eng. 2020 ;4(1):111-124., DOI:
10.1038 /s41551-019-0505-1
4. Kim HK, Kim Y, Lee S, Min S, Bae JY,
Choi JW, Park J, Jung D, Yoon S, Kim H+
(+Corresponding author). SpCas9 activity
prediction by DeepSpCas9, a deep learning
? based model with high generalization performance.
Sci. Adv. 2019; 5 (11): eaax9249, DOI: 10.1126/sciadv.aax9249
5. Kim HK, Min S, Song M, Jung S, Choi
JW, Kim Y, Lee S, Yoon S+, Kim H+ (+Corresponding
authors). Deep learning improves prediction
of CRISPR?Cpf1 guide RNA activity.
Nat. Biotechnol. 2018; 36(3):239-241.
6. Kim W, Lee S, Kim HS, Song M, Cha YH,
Kim YH, Shin J, Lee ES, Joo Y, Song JJ,
Choi EJ, Choi JW, Lee J, Kang M, Yook JI,
Lee MG, Kim YS, Paik S, Kim H+ (+Corresponding
author). Targeting mutant KRAS with CRISPR-Cas9
controls tumor growth.
Genome Res. 2018; 28: 374-382.
7. Gopalappa R, Suresh B, Ramakrishna S+,
Kim H+ (+Corresponding authors). Paired
D10A Cas9 nickases are sometimes more efficient
than individual nucleases for gene disruption.
Nucleic Acids Res. 2018; 46(12):e71.
8. Lim JS, Gopalappa R, Kim SH, Ramakrishna
S, Lee M, Kim W, Kim J, Park SM, Lee J,
Oh JH, Kim HD, Park CH, Lee JS, Kim S, Kim
SD, Han JM, Kang HC+, Kim H+, Lee JH+ (+Corresponding
authors). Somatic Mutations in TSC1 and
TSC2 cause focal cortical dysplasia.
Am. J. Hum. Genet. 2017;100(3) :454-472.
9. Kim HK, Song M, Lee J, Menon AV, Jung
S, Kang YM, Choi JW, Woo E, Koh HC, Nam
JW, Kim H+ (+Corresponding author). In vivo
high-throughput profiling of CRISPR-Cpf1
activity.
Nat. Methods. 2017; 14(2):153-159.
10. Kim YH, Kim HO, Baek EJ, Kurita R,
Cha HJ, Nakamura Y, Kim H+ (+Corresponding
author). Rh D blood group conversion using
transcription activator-like effector nucleases.
Nat. Commun., 2015; 6:7451.
11. Ramakrishna S, Dad A-B D, Beloor J,
Gopalappa R, Lee S-K, Kim H+ (+Corresponding
author). Gene disruption by cell-penetrating
peptide-mediated delivery of Cas9 protein
and guide RNA.
Genome Res., 2014; 24(6):1020-7. (Featured
on the cover).
12. Kim H, Kim JS. A guide to genome engineering
with programmable nucleases.
Nat. Rev. Genet., 2014; 15 (5): 321-334.
13. Ramakrishna S, Cho SW, Kim S, Song
M, Gopalappa R, Kim JS+, Kim H+ (+Corresponding
authors). Surrogate reporter-based enrichment
of cells containing RNA-guided Cas9 nuclease-induced
mutations.
Nat. Commun., 2014; 5: 3378.
14. Kim H, Um E, Cho SR, Jung C, Kim H+,
and Kim JS+ (+Corresponding authors). Surrogate
reporters for enrichment of cells with nuclease-induced
mutations.
Nat. Methods, 2011; 8: 941-3.
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