교수, M.D., Ph.D. 연세대학교
  유전체교정, 유전자치료, 줄기세포
  2228-0879
  hkim1@yuhs.ac
 
 


1. Kim HK, Min S, Song M, Jung S, Choi JW, Kim Y, Lee S, Yoon S+, Kim H+ (+Corresponding author). Deep learning improves prediction of CRISPR?Cpf1 guide RNA activity. Nat Biotechnol. 2018.

2. Kim W, Lee S, Kim HS, Song M, Cha YH, Kim YH, Shin J, Lee ES, Joo Y, Song JJ, Choi EJ, Choi JW, Lee J, Kang M, Yook JI, Lee MG, Kim YS, Paik S, Kim H+ (+Corresponding author). Targeting mutant KRAS with CRISPR-Cas9 controls tumor growth. Genome Res. 2018

3.Gopalappa R, Suresh B, Ramakrishna S+, Kim H+ (+Corresponding authors). Paired D10A Cas9 nickases are sometimes more efficient than individual nucleases for gene disruption. Nucleic Acids Res. 2018.

4. Kim HK, Song M, Lee J, Menon AV, Jung S, Kang YM, Choi JW, Woo E, Koh HC, Nam JW, Kim H+ (+Corresponding author). In vivo high-throughput profiling of CRISPR-Cpf1 activity. Nat. Methods., 2017; 14: 153-159

5.Lim JS, Gopalappa R, Kim SH, Ramakrishna S, Lee M, Kim W, Kim J, Park SM, Lee J, Oh JH, Kim HD, Park CH, Lee JS, Kim S, Kim SD, Han JM, Kang HC+, Kim H+, Lee JH+ (+Corresponding authors). Somatic Mutations in TSC1 and TSC2 cause focal cortical dysplasia. Am J Hum Genet. 2017 ;100(3) :454-472

6. Kim YH, Kim HO, Baek EJ, Kurita R, Cha HJ, Nakamura Y, Kim H+ (+Corresponding author). Rh D blood group conversion using transcription activator-like effector nucleases. Nat. Commun., 2015 Jun 16; 6:7451.

7. Ramakrishna S, Dad A-B D, Beloor J, Gopalappa R, Lee S-K, Kim H+ (+Corresponding author). Gene disruption by cell-penetrating peptide-mediated delivery of Cas9 protein and guide RNA. Genome Res., 2014 June. 24: 1020-1027

8. Kim H, Kim JS. A guide to genome engineering with programmable nucleases. Nat. Rev. Genet., 2014 May;15(5):321-34.

9. Ramakrishna S, Cho SW, Kim S, Song M, Gopalappa R, Kim JS+, Kim H+ (+Corresponding authors). Surrogate reporter-based enrichment of cells containing RNA-guided Cas9 nuclease-induced mutations. Nat. Commun., 2014 Feb 26; 5: 3378.

10. Kim H, Um E, Cho SR, Jung C, Kim H+, and Kim JS+ (+Corresponding authors). Surrogate reporters for enrichment of cells with nuclease-induced mutations. Nat. Methods, 2011 Oct 9;8:941-3.




 
 
 
 
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